Search on: CDK2 ASSOCIATED PROTEIN 20 KDA 
Descriptors Found: 1
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Descriptor English:   Cyclin-Dependent Kinase Inhibitor p21 
Descriptor Spanish:   Inhibidor p21 de las Quinasas Dependientes de la Ciclina 
Descriptor Portuguese:   Inibidor de Quinase Dependente de Ciclina p21 
Synonyms English:   CDK2-Associated Protein 20 kDa
CDKN1 Protein
CDKN1A Protein
Cdk-Interacting Protein 1
Cdk2 Inhibitor Protein
Cell Cycle Regulator p21
Cyclin Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor 1A Protein
Senescent Cell-Derived Inhibitor Protein 1
p21 Cell Cycle Regulator
p21 Cyclin Kinase Inhibitor
CDK2 Associated Protein 20 kDa
Cdk Interacting Protein 1
Cyclin Dependent Kinase Inhibitor 1A Protein
Cyclin Dependent Kinase Inhibitor p21
Senescent Cell Derived Inhibitor Protein 1  
Tree Number:   D12.644.360.225.500
D12.776.167.187.500
D12.776.476.225.500
D12.776.624.776.355.500
Definition English:   A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3. 
Pharmacological Action:   Protein Kinase Inhibitors
 
History Note English:   2006(1993) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50931 
Unique Identifier:   D050759 

Occurrence in VHL:
 

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